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The Women’s Bone Health Institute

I Took Calcium, Vitamin D & K Every Day For 8 Years. My DEXA Scan Said Otherwise... Here's What My Doctor Never Told Me.

By Sarah Martinez | June 4, 2025 | 13 Minute Read

My name is Sarah Martinez. I'm 53 years old.

And up until last year, I thought I was doing everything right for my bones.

I took calcium citrate, vitamin D3, and K2 every single morning for eight years... Never missed a day.

I ate yogurt. Drank milk. Loaded up on leafy greens.

I did yoga three times a week. Took long walks. Lifted light weights.

My doctor always said I was a model patient.

So when she recommended a routine bone density scan after I turned 52, I wasn't worried at all.

I figured it would just confirm what I already knew. My bones were fine.

Then I got the call...

The Phone Call That Changed Everything

"Sarah, we need to talk about your results."

My doctor's voice was different... Serious.

"Your lumbar spine T-score is negative 2.3. That's osteopenia, borderline osteoporosis."

I sat down hard in my kitchen chair.

"But... how could this happen to me? I take calcium every single day. I'm too young for this. This doesn't make sense."

My doctor was quiet for a moment.

"Sometimes calcium and vitamin D aren't enough. We should really talk about medication. I'm going to prescribe Fosamax."

That night, I couldn't sleep. I was so frustrated. I kept thinking about my grandmother. How one fall put her in a wheelchair. How she never recovered.

I was terrified of fractures.

But I Was About To Become Even More Terrified Of The So-Called Solution...

What I found about bisphosphonates like Fosamax & Prolia made my stomach turn...

Jaw necrosis. Where your jawbone literally dies and rots away.

Atypical femur fractures. Your thigh bone just snaps in half while you're walking.

And the kicker? These drugs don't even build new bone. They just freeze your bone cycle in place.

I called my doctor back.

"I can't take these. The side effects are worse than the disease."

"Then I don't know what else to tell you, Sarah. Just keep taking your calcium."

I hung up feeling completely trapped. Scared of fractures. Scared of drugs. Scared of not doing anything. Angry that eight years of doing everything right had been completely wasted.

"Women can lose up to 20% of their bone mass in the 5-10 years after menopause.” (CDC, 2021)

I was already behind, and nothing my doctor offered was actually going to rebuild what I'd lost.

Late Night Research Led Me To A Doctor Who Finally Told The Truth

Three weeks later, at 2 AM, I was still searching online.

"Why doesn't calcium work for osteoporosis?"

That's when I found an article by Dr. Marcus Chen.

The headline stopped me cold:

"After 20 Years In Big Pharma, I Finally Admitted The Truth: We Were Treating The Wrong Problem Entirely"

I started reading and everything changed...

What Dr. Chen Revealed

(And Why It Made My Blood Boil)

Here's what Dr. Chen wrote.

I'm sharing it word-for-word because every woman needs to hear this:

"For decades, the drugs prescribed to women with osteoporosis weren’t designed to rebuild bone.

Other than very risky anabolic drugs for the worst cases, they just tried to freeze the damage.

And the risks were rarely discussed up front.

I told myself it wasn’t my place to question it.

I could have stayed quiet. Kept doing my job.

Kept collecting a paycheck. Until it became personal.

My own mother became part of the statistics...

That's when I found that the real problem went far deeper than anyone wanted to admit.

But before I elaborate, you need to understand something first.

You need to know what's really happening inside your bones."

And then Dr. Chen explained something my doctor never mentioned...

Your bones have two types of cells:

Osteoclasts - These break down old bone. Think of them as the demolition crew.

Osteoblasts - These build new bone. They're the construction crew.

When you're young, these crews work in perfect balance. Old bone out, new bone in.

But during menopause, everything goes haywire.

The Real Reason Your Bones Are Crumbling

(It's Not What You Think)

Dr. Chen explained it like this:

Estrogen is the boss that keeps the demolition crew in check.

When estrogen drops during menopause, the demolition crew goes into overdrive. No boss to stop them.

They start tearing down bone faster than the builders can replace it.

Most people would assume an easy fix is to raise estrogen levels…

But unfortunately, it's not that simple.

Raising it through Hormone Replacement Therapy (HRT) of course comes with its own set of problems like:

Increased risk of blood clots
Breast cancer concerns
Heart issues

But that's not all what shocked me:

The real problem isn't just the demolition crew running wild.

The construction crew is exhausted.

They've run out of energy.

And this is where calcium completely fails.

⚠️ The Dark Side of Calcium

Think of calcium like bricks sitting on a construction site.

You can pile up all the bricks you want. However, if your construction workers have no energy to pick them up and lay them down, nothing gets built.

That's exactly what's happening in your bones.

All the materials in the world won't help if you have no energy...

Your builders literally don't have the energy to use the calcium and vitamin D you're taking.

That's why you can take calcium & vitamin D for years and still lose bone density.

But here's the kicker:

When your body has too much calcium... it begins to build up in the blood.

It can lead to deposits in the walls of your arteries, creating calcified blockages which strain your kidneys.

For some, that ends in kidney stones.

For others… it ends in something far worse.

Later Dr. Chen wrote something that made me want to cry:

"For decades, we told women the problem was calcium deficiency. We were wrong. The problem is cellular energy deficiency."

I sat at my kitchen table at 2 AM, reading this. And I started crying.

Not sad tears. Angry tears.

How many years had I wasted? How much bone density had I lost that I could have saved?

But then Dr. Chen shared something that gave me hope for the first time in weeks.

The Discovery That Changed Everything

Dr. Chen's research led him to a small group of islands in Japan.

Okinawa.

Women there stay strong into their 70s and 80s. They don't live in fear of fractures.

Scientists wanted to know why.

What they found was shocking:

Okinawan women naturally maintain up to 45% higher levels of this molecule called NAD+ their entire lives.

NAD+ is an essential coenzyme found in every living cell, that plays a crucial role in cellular function.

Think of it like the battery that powers all trillion cells in your body.

And as you get older your bone-building cells need massive amounts of it to do their job.

But after age 40, your NAD+ levels drop by up to 50%.

It turns out that the Okinawan women have figured out the secret.

They eat foods loaded with NAD+, purple sweet potatoes, fermented soybeans, and fresh fish.

Their bone-building cells stay charged, which means their bones stay strong.

They also live in cleaner environments with less pollution. Less oxidative stress draining their cellular energy.

The result? 40% fewer hip fractures than American women. But here's the problem for the rest of us.

We can't eat like Okinawans.

Our food supply is polluted with pesticides and toxins. Our stress is higher. Our air quality is worse.

Our NAD+ gets drained faster than ever before.

Dr. Chen realized something important:
If we could restore NAD+ levels directly, we could give the bone-building cells the energy they desperately need.

And that's exactly why Big Pharma keeps pushing drugs that never fix the real problem.

They profit off keeping women trapped on medications that only slow damage, never heal it.

Why Drugs Will Never Fix The Real Problem

Dr. Chen explained something that finally made sense of why antiresorptive drugs have such terrible track records:

"Bisphosphonates like Fosamax slow bone loss by stopping your demolition crew. But they do nothing to build new bone."

"Worse, long-term use can create "frozen bone" that becomes brittle. That's why women on these drugs for years still fracture."

This explained everything. The drugs my doctor wanted to prescribe would never actually rebuild my bones.

They'd just trap them in a state of suspended decay.

That's When Dr. Chen Revealed The Real solution.

Similarly, years ago, Dr. Chen’s mother was prescribed only these drugs and told to just increase her calcium intake.

This was after her surprise osteoporosis diagnosis…

She had shattered her ankle just stepping off a curb in the parking lot... with zero prior symptoms.

She was devastated. Debilitating. Depressing. Dr. Chen watched his mother's world collapse overnight.

Dr. Chen became furious.

Not at his mother. At a system that let this happen. A system that called it "silent disease" and then acted shocked when women broke bones from everyday life.

When Dr. Chen quit his 20-year position at a major pharmaceutical company.

He teamed up with three trusted colleagues to figure out a the best way to raise NAD+ levels directly.

Firstly, after testing they found that NAD+ doesn't work alone. You need three things working together: NAD+, Resveratrol & Quercetin.

Together, these 3 ingredients create a complete system:

Restores energy to the osteoblasts.
Activate the bone-builders.
Calms the osteoclasts.

After Testing: Dr Chen Gave This Blend To His Mother

After a few months passed, his mother called him crying saying...

"Last Saturday, little Miko asked me to chase him around the backyard. I actually did it. I jogged. I didn't limp. I didn't hold my breath waiting for pain. I just moved like a normal grandmother."

That's when Dr. Chen knew they had it.

He called it Thryve.

I sat at my kitchen table, reading his research papers. Looking at the actual published studies.

Real women. Real results. Published science in peer-reviewed journals.

I thought about my next bone scan in six months.

I thought about my grandmother in that wheelchair.

I thought about being too scared to pick up my future grandchildren.

At some point, I started crying.

My husband found me sitting there, papers spread across the table.

“What happened?” he asked.

"I think I finally found an answer," I told him. "I'm just scared to hope again."

He put his hand on my shoulder. "Then test it. What do you have to lose?"

He was right.

So I gave myself six months, one last try before accepting defeat.

What Happened In The First 2 Months Surprised Me

I'm not going to lie and say it was instant magic.

The first week, I felt... nothing. I almost gave up.

But around week 3, I noticed something small.

I woke up without my usual morning stiffness.

Getting out of bed didn't require the slow, painful roll-and-push routine I'd developed.

I could just... stand up. Like a normal person.

By week 5, my knee pain during yoga was noticeably better.

I could hold poses I'd been modifying for months.

Downward dog didn't make my wrists ache. And especially warrior pose didn't make my back throb.

Week 6 is when my husband noticed.

"You're moving differently," he said. "Like you're not scared of your own body anymore."

He was right.

I'd been tiptoeing through my own life. Afraid every movement might cause a fracture.

That constant fear was starting to lift.

Month 4: The Confidence Started Coming Back

By month 4, I was doing things I'd stopped doing.

I carried a full laundry basket up the stairs. Both hands. No fear.

I reached up to get something from the top shelf without that moment of hesitation and mental calculation.

I went for a hike with my sister. A real hike with elevation, not a gentle walk on flat ground.

My daughter called and asked if I wanted to help her move furniture for her new apartment.

A few months ago, I would have made an excuse. Now I said yes.

The physical changes were obvious.

But the emotional shift was even bigger.

I felt like myself again.

Not some fragile version of myself. Not some old lady waiting to break.

Just... me. Sarah. The person I was before that devastating phone call.

My adult son Hunter noticed it during Friday night dinner.

"Mom, you seem happier," he said. "More like your old self."

I didn't realize how much fear I'd been carrying until I finally let it go.

My Latest DEXA Scan That Made Me Cry

My follow-up DEXA scan was scheduled for next February.

I was terrified the night before.

What if nothing had changed? What if I'd just wasted another six months?

What if my hope had been stupid and naive? The next morning, the technician did the scan.

Then my doctor came in to review the results.

She pulled up my scans side by side on the screen. My old scan from August last year. The new one from February.

She looked at the screen. Then looked at me. Then back at the screen.

"Sarah, your T-score improved to negative 1.9. You've gained bone density."

I started crying right there in her office...

I went from borderline osteoporosis back to moderate osteopenia in record time.

My bones demolition crew was still active, but my bone's construction crew had finally woken up.

They had the energy to rebuild again.

The 90-Day Guarantee That Removes All Risk

Dr. Chen's company offers something no drug company ever would:

Try Thryve for 90 days. If you see 0 improvement in the way you feel or your next bone scan doesn't show improvement, they'll refund every penny.

No questions asked. No hassle. No keeping the bottles or jumping through hoops. They can offer this because the science works.

Think about it: What does your doctor's option offer?

Bisphosphonates with no guarantee they'll work. A long list of terrifying side effects. And if they don't work or you can't tolerate them, you're back where you started - but with weaker bones.

Thryve offers you a genuine 90-day trial with your money back if it doesn't deliver.

That's the difference between a company that profits from keeping you dependent on drugs forever, and a company that stands behind its science.

And The Best Part?

Thryve's simple and natural formula works at the cellular level, meaning it won’t interfere with any medications, treatments, or supplements you're currently taking.

Thanks to NAD+, your body actually gains the energy it needs to fully utilize your bone-supporting supplements like calcium, magnesium, vitamin D3, and K2 to their full potential.

Just three powerhouse ingredients, encased in an easy-to-swallow vegetable capsule and made here in the USA in an FDA and GMP-registered facility, which will be shipped straight to your door.

How To Get Thryve

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Real Women Share Their Thryve Results

Overall Rating: 4.7/5 stars (Based on 274 reviews)

Even My Hairdresser Noticed!"

Even my hairdresser noticed how great my skin looked and couldn't believe I'm 57 years old. My afternoon fatigue is completely gone—I used to crash every day around 2 PM and now I have steady energy until evening.

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"Natural Energy Without Jitters"

But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth

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"Better Sleep, Better Everything"

My sleep tracker shows significant improvement in deep sleep quality. According to my data, I feel like my circadian rhythm is back to a natural state. I've been having trouble sleeping for years due to shift work.

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"My Skin Texture Is Incredible"

The fine lines around my eyes have visibly softened, and people keep asking what I'm doing differently. I've been taking it for 4 months now and the changes just keep getting better.

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Frequently Asked Questions

About NAD+ and How It Works

What exactly is NAD+ and why do I need it?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every single one of your 30 trillion cells. Think of it as the "fuel" that powers your cellular engines (mitochondria), drives DNA repair, and activates longevity proteins called sirtuins.

After age 40, your NAD+ levels can drop by up to 50%, which is why you start feeling tired, recovering slower, and aging faster. It's not just "getting older"—your cells are literally running out of fuel.

How is this different from other energy supplements or vitamins?

Most energy supplements rely on stimulants like caffeine that give you a temporary boost followed by a crash. Thryve works at the cellular level to restore your body's natural energy production system. It's like the difference between jump-starting a car with a dead battery versus actually replacing the battery.

What makes Thryve different from other NAD+ supplements?

Three key differences:

Direct NAD+ delivery - We use pure NAD+, not just precursors that may not convert properly, especially during perimenopause when enzyme activity changes
Female-specific formula - Includes quercetin to clear "zombie" cells that cause wrinkles, and resveratrol to activate longevity pathways
Enhanced absorption - Our liposomal delivery system ensures the NAD+ actually reaches your cells instead of being broken down in your stomach

Safety and Side Effects

Is it safe to take long-term?

Yes. NAD+ is not a foreign substance—it's a molecule your body naturally produces. Clinical studies, including a landmark trial at Chiba University, have shown NAD+ supplementation to be safe for long-term use. In fact, maintaining healthy NAD+ levels is essential for healthy aging.

Are there any side effects?

The vast majority of women experience no negative side effects. In rare cases (less than 5% of users), some people report mild digestive upset when first starting. This typically resolves within a few days as your body adjusts. We recommend taking with food if you have a sensitive stomach.

Can I take this if I'm on other medications or supplements?

NAD+ is generally safe to combine with other supplements and medications. However, if you're taking prescription medications, especially blood thinners or diabetes medications, consult your healthcare provider before starting any new supplement regimen.

What if I'm pregnant or breastfeeding?

While NAD+ is naturally present in your body, we recommend consulting your healthcare provider before taking any supplements during pregnancy or breastfeeding.

Results and Timeline

How quickly will I see results?

Most women notice increased energy within the first 1-2 weeks. Skin improvements typically become visible around weeks 4-6.

Deeper benefits like improved recovery, better sleep, and joint comfort often develop over 2-3 months as your cellular NAD+ levels rebuild.

Remember, this isn't a quick fix—it's restoring your cellular function, which takes time but creates lasting results.

What if I don't see results right away?

NAD+ works at the cellular level, so changes build over time. Some women with severely depleted NAD+ levels may need 4-6 weeks to notice significant improvements. We offer a 60-day money-back guarantee specifically because we know some women need more time to experience the full benefits.

Will the benefits go away if I stop taking it?

Your NAD+ levels will gradually return to their previous state if you stop supplementing, since the age-related decline continues. However, the cellular repair and improvements that occurred while taking Thryve don't instantly disappear—think of it like exercise. You'll maintain some benefits, but consistency gives you the best long-term results.

Dosage and Usage

How much should I take and when?

Take 2 capsules daily with your first meal. Taking with food helps with absorption and reduces any potential stomach sensitivity.

Some women prefer taking both in the morning, while others split the dose (1 morning, 1 evening). Find what works best for your routine.

Can I take more than the recommended dose?

Stick to the recommended dosage. More isn't necessarily better with NAD+, and our formula is precisely dosed based on clinical research. Taking excessive amounts won't accelerate results and may cause unnecessary digestive upset.

Do I need to cycle off or take breaks?

No cycling necessary. NAD+ is something your body needs consistently, and the age-related decline is ongoing. Consistent daily use provides the best results for maintaining healthy cellular function.

Specific Health Concerns

I'm in perimenopause/menopause. Will this help with my symptoms?

Many of the symptoms women experience during hormonal transitions—fatigue, brain fog, poor sleep, mood swings—are actually related to declining NAD+ levels.

Hormonal changes can accelerate NAD+ depletion, which is why we specifically formulated Thryve for women 40+. Many customers report improvements in energy, sleep quality, and mental clarity.

Will this help with my joint pain and stiffness?

While we can't make medical claims, the research on NAD+ and cellular repair is promising. Many customers report improved recovery and reduced stiffness. The quercetin in our formula has been studied for its effects on the enzymes that break down cartilage.

I have chronic fatigue. Is this different from other things I've tried?

If your fatigue is related to cellular energy production (which is common), NAD+ addresses the root cause rather than just masking symptoms. Many women with long-standing fatigue have found relief when other approaches failed, because this works at the mitochondrial level where energy is actually made.

Can this help with weight management?

NAD+ plays a role in metabolism, and many customers report improved energy for exercise and better sleep (both important for weight management).

However, Thryve is not specifically a weight loss supplement—it's designed to restore cellular function, which can support overall health and vitality.

Ordering and Guarantee

How long does shipping take?

We offer free shipping on all orders, with standard delivery in 3-5 business days within the US. Express shipping options are available at checkout for faster delivery.

What's your return policy?

We offer a 30-day money-back guarantee. If you're not completely satisfied with your results, return the bottles (even if empty) within 60 days for a full refund. No questions asked.

Do you offer subscriptions or bulk discounts?

Yes! Our subscription program offers 15% savings and ensures you never run out. You can modify or cancel anytime. We also offer bundle discounts for 3 and 6-month supplies.

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The women who feel and look 10 years younger than their age aren't lucky. They're not genetically blessed.

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References

Centers for Disease Control and Prevention (CDC). (2021). Prevalence of osteoporosis at the femur neck or lumbar spine among older adults: United States, 2017–2018. National Center for Health Statistics Data Brief, No. 405.
https://www.cdc.gov/nchs/products/databriefs/db405.htm

Chen, X., et al. (2024). Role of androgens in bone metabolism and osteoclast regulation. International Journal of Molecular Sciences, 25(22), 12139.
https://www.mdpi.com/1422-0067/25/22/12139

Khosla, S., et al. (2017). OPG/RANK/RANKL signaling in bone remodeling. Molecular Medicine Reports, 15(5), 2529–2537.
https://www.spandidos-publications.com/10.3892/mmr.2017.6168

Boyce, B. F., & Xing, L. (2008). The RANK–RANKL–OPG pathway. Journal of Clinical Investigation, 118(8), 2803–2812.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10608105/

Rachner, T. D., Khosla, S., & Hofbauer, L. C. (2011). Osteoporosis: Now and the future. The Lancet, 377(9773), 1276–1287.
https://www.longdom.org/open-access/postmenopausal-osteoporosis-causes-mechanisms-risks-diagnosis-treatment-and-prevention-guide1103308.html

Eastell, R., et al. (2022). Pathophysiology of postmenopausal osteoporosis. Journal of Bone and Mineral Research.
https://pubmed.ncbi.nlm.nih.gov/35193674/

Verdin, E. (2015). NAD⁺ in aging, metabolism, and neurodegeneration. Science, 350(6265), 1208–1213.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12338550/

Zhu, X., et al. (2015). Age-related decline of NAD⁺ in human tissues. Cell Metabolism, 21(3), 410–421.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7442590/

Elhassan, Y. S., et al. (2019). NAD⁺ metabolism in aging populations. Nature Metabolism, 1(10), 1046–1055.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3139257/

López-Otín, C., et al. (2024). Mitochondrial dysfunction and skeletal aging. Aging Cell.
https://pubmed.ncbi.nlm.nih.gov/40053115/

Endocrine Society. (n.d.). Menopause and bone loss.
https://www.endocrine.org/patient-engagement/endocrine-library/menopause-and-bone-loss

Compston, J. E., et al. (2019). Osteoporosis. The Lancet, 393(10169), 364–376.
https://pubmed.ncbi.nlm.nih.gov/32564438/

Khosla, S., Oursler, M. J., & Monroe, D. G. (2012). Estrogen and the skeleton. Trends in Endocrinology & Metabolism, 23(11), 576–581.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12338550/

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