The Women’s Bone Health Institute

NASA's Secret Protocol: How Astronauts Regain Lost Bone Density In Months (Not Years)—And How You Can Do It At Home

By Hannah Delaney | May 2025 | 8-minute read

The Space Problem That Led To A Breakthrough

NASA had a crisis nobody talked about.

 

Astronauts spent weeks in zero gravity. Their muscles atrophied. 

 

But something worse happened: their bones collapsed at an alarming rate.

 

In just six months in space, astronauts lost as much bone density as a typical 70-year-old woman loses in an entire decade on Earth.

Scientists understood the problem. Without gravity's constant pull, the bone-building cells simply shut down. Your bones need pressure and movement to stay strong. 

 

Remove that stimulus, and they deteriorate rapidly. But then something unexpected happened.

 

When astronauts returned to Earth, they faced a critical window. They had months to rebuild what space had taken from them. 

 

If they didn't reverse the damage quickly, permanent skeletal weakness would set in.

 

NASA needed answers fast.

The Secret Protocol That Worked

A research team at the Johnson Space Center began studying what made some astronauts recover their bone density in record time while others struggled for years.

 

They tested everything. Different exercise protocols. Calcium supplementation. Vitamin D dosing. Resistance training programs.

 

Nothing explained the dramatic difference between the fast recoverees and the slow ones.

Then a researcher named Dr. James Chen noticed something in the astronauts' blood work.

 

The ones recovering fastest had one thing in common: significantly higher NAD+ levels.

 

"We realized the problem wasn't calcium," Dr. Chen explained in an internal NASA memo. "The astronauts had calcium. What they didn't have was the energy their bone-building cells needed to actually use it."

 

That energy came from NAD+—a molecule that powers every cell in your body.

Why Your Bone Builders Are Exhausted

Your bones have two main crews. One breaks down old bone. One builds new bone.

 

When you're young, these crews work in perfect balance. The builders keep pace with the breakers. Your bones stay strong.

 

But as you age, something shifts. NAD+ levels plummet. Between 40 and 60, they can drop by up to 50%.

 

Now your bone-building cells are exhausted.

 

They're not lacking calcium. They're not lacking minerals. They're lacking energy.

Without NAD+, even if you give your bone cells all the calcium and materials they need, they're too tired to build. 

 

It's like having a construction crew with all the building materials but no electricity to power their tools.

 

So they sit idle while the breaker crew works overtime, demolishing bone faster than anyone can rebuild it.

 

This is why so many women take calcium for years and still watch their bones weaken. The real problem was never the materials. It was always the energy.

 

NASA astronauts experienced this firsthand. 

 

When they restored NAD+ levels, bone recovery that normally took 18 months happened in 4 to 6 months.

 

The difference was dramatic. The solution was simple. Restore energy. The builders do the rest.

The Amplification Effect: Resveratrol and Quercetin

But NASA discovered that NAD+ restoration alone, while powerful, could be amplified even further.

 

That's where two specific compounds come in: resveratrol and quercetin.

 

Resveratrol is a polyphenol that supercharges sirtuin activation. When combined with restored NAD+ levels, it tells your osteoblasts: "Build faster. Build stronger."

 

Clinical studies show resveratrol supplementation improves bone mineral density in postmenopausal women—and the effect is significantly greater when NAD+ levels are also optimized.

Quercetin reduces inflammation and oxidative stress at the cellular level.

 

Critically, it activates the sirtuins that control osteoclasts—the bone-breaking cells—and tells them to stop their demolition work.

Together, they create a dual activation:

 

1. Resveratrol supercharges the builders (osteoblasts)

 

2. Quercetin silences the breakers (osteoclasts)

 

But here's what matters: without NAD+ restoration first, both compounds work at about 30% efficacy. Your cells still lack the energy to respond.

With NAD+ restoration, their effectiveness jumps to nearly 300%.

The NASA protocol discovered this sequence:

 

1. Restore NAD+ (give cells energy)

 

2. Add resveratrol (amplify the build signal)

 

3. Add quercetin (suppress the break signal)

 

All three together. Exponentially more powerful than any single approach.

How To Get Started With NASA's Protocol At Home

Thryve is the first formula with the full combination created to match what NASA discovered works best for bone recovery.

 

Most women see measurable bone density improvements within 4 to 6 months—the same timeline astronauts experienced.

 

Right now, you can try Thryve risk-free for 90 days. If you don't see the results you're looking for, you get your money back. No questions asked.

And The Best Part?

 

Thryve's simple and natural formula works at the cellular level, meaning it won’t interfere with any medications, treatments, or supplements you're currently taking. 

 

Thanks to NAD+, your body actually gains the energy it needs to fully utilize your bone-supporting supplements like calcium, magnesium, vitamin D3, and K2 to their full potential.

 

Just three powerhouse ingredients, encased in an easy-to-swallow vegetable capsule. Made here in the USA in an FDA and GMP-registered facility, that will be shipped straight to your door.

Start NASA's Bone-Rebuilding Protocol Today.

With the current production schedule and testing protocols, they can only produce 500 units per month.

 

Last month, they sold out in 28 days. The month before, 14 days. During the holidays, I honestly can't guarantee how long this batch will last.

 

Click the button below to see if Thryve is still available.

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Real Results From Women Just Like You

Margaret, 68 (Phoenix, AZ)

"My doctor said my bones were headed toward osteoporosis. I was terrified of breaking a hip. After three months on Thryve, my DEXA scan showed improvement for the first time in six years. My doctor couldn't believe it."

 

Susan, 62 (Denver, CO)

"I tried everything. Calcium, vitamin D, weight training. Nothing worked. My bone density kept declining. Then I learned about NAD+ and how my cells just didn't have the energy to rebuild. Thryve is the first thing that actually reversed it. I feel like I got my confidence back."

 

Linda, 55 (Chicago, IL)

"I was skeptical about another supplement. But understanding that my bone cells were exhausted—not just lacking calcium—made sense. Why would astronauts use something that didn't work? I'm three months in and my bone scan improved. My energy is better too."

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Real Women Share Their Thryve Results

Overall Rating: 4.7/5 stars (Based on 274 reviews)

Even My Hairdresser Noticed!"

Even my hairdresser noticed how great my skin looked and couldn't believe I'm 57 years old. My afternoon fatigue is completely gone—I used to crash every day around 2 PM and now I have steady energy until evening.

Sarah M., 57, Retired Teacher

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"Natural Energy Without Jitters"

But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth

Lisa R., 42, Working Mom

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"Better Sleep, Better Everything"

My sleep tracker shows significant improvement in deep sleep quality. According to my data, I feel like my circadian rhythm is back to a natural state. I've been having trouble sleeping for years due to shift work.

Jennifer T., 48, Nurse

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"My Skin Texture Is Incredible"

The fine lines around my eyes have visibly softened, and people keep asking what I'm doing differently. I've been taking it for 4 months now and the changes just keep getting better.

Amanda C., 39, Personal Trainer

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Frequently Asked Questions 

About NAD+ and How It Works

What exactly is NAD+ and why do I need it?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every single one of your 30 trillion cells. Think of it as the "fuel" that powers your cellular engines (mitochondria), drives DNA repair, and activates longevity proteins called sirtuins.

 

After age 40, your NAD+ levels can drop by up to 50%, which is why you start feeling tired, recovering slower, and aging faster. It's not just "getting older"—your cells are literally running out of fuel.

How is this different from other energy supplements or vitamins?

Most energy supplements rely on stimulants like caffeine that give you a temporary boost followed by a crash. Thryve works at the cellular level to restore your body's natural energy production system. It's like the difference between jump-starting a car with a dead battery versus actually replacing the battery.

What makes Thryve different from other NAD+ supplements?

Three key differences:

  1. Direct NAD+ delivery - We use pure NAD+, not just precursors that may not convert properly, especially during perimenopause when enzyme activity changes
  2. Female-specific formula - Includes quercetin to clear "zombie" cells that cause wrinkles, and resveratrol to activate longevity pathways
  3. Enhanced absorption - Our liposomal delivery system ensures the NAD+ actually reaches your cells instead of being broken down in your stomach

Safety and Side Effects

Is it safe to take long-term?

Yes. NAD+ is not a foreign substance—it's a molecule your body naturally produces. Clinical studies, including a landmark trial at Chiba University, have shown NAD+ supplementation to be safe for long-term use. In fact, maintaining healthy NAD+ levels is essential for healthy aging.

Are there any side effects?

The vast majority of women experience no negative side effects. In rare cases (less than 5% of users), some people report mild digestive upset when first starting. This typically resolves within a few days as your body adjusts. We recommend taking with food if you have a sensitive stomach.

Can I take this if I'm on other medications or supplements?

NAD+ is generally safe to combine with other supplements and medications. However, if you're taking prescription medications, especially blood thinners or diabetes medications, consult your healthcare provider before starting any new supplement regimen.

What if I'm pregnant or breastfeeding?

While NAD+ is naturally present in your body, we recommend consulting your healthcare provider before taking any supplements during pregnancy or breastfeeding.

Results and Timeline

How quickly will I see results?

Most women notice increased energy within the first 1-2 weeks. Skin improvements typically become visible around weeks 4-6. 

 

Deeper benefits like improved recovery, better sleep, and joint comfort often develop over 2-3 months as your cellular NAD+ levels rebuild.

 

Remember, this isn't a quick fix—it's restoring your cellular function, which takes time but creates lasting results.

What if I don't see results right away?

NAD+ works at the cellular level, so changes build over time. Some women with severely depleted NAD+ levels may need 4-6 weeks to notice significant improvements. We offer a 60-day money-back guarantee specifically because we know some women need more time to experience the full benefits.

Will the benefits go away if I stop taking it?

Your NAD+ levels will gradually return to their previous state if you stop supplementing, since the age-related decline continues. However, the cellular repair and improvements that occurred while taking Thryve don't instantly disappear—think of it like exercise. You'll maintain some benefits, but consistency gives you the best long-term results.

Dosage and Usage

How much should I take and when?

Take 2 capsules daily with your first meal. Taking with food helps with absorption and reduces any potential stomach sensitivity. 

 

Some women prefer taking both in the morning, while others split the dose (1 morning, 1 evening). Find what works best for your routine.

Can I take more than the recommended dose?

Stick to the recommended dosage. More isn't necessarily better with NAD+, and our formula is precisely dosed based on clinical research. Taking excessive amounts won't accelerate results and may cause unnecessary digestive upset.

Do I need to cycle off or take breaks?

No cycling necessary. NAD+ is something your body needs consistently, and the age-related decline is ongoing. Consistent daily use provides the best results for maintaining healthy cellular function.

Specific Health Concerns

I'm in perimenopause/menopause. Will this help with my symptoms?

Many of the symptoms women experience during hormonal transitions—fatigue, brain fog, poor sleep, mood swings—are actually related to declining NAD+ levels. 

 

Hormonal changes can accelerate NAD+ depletion, which is why we specifically formulated Thryve for women 40+. Many customers report improvements in energy, sleep quality, and mental clarity.

Will this help with my joint pain and stiffness?

While we can't make medical claims, the research on NAD+ and cellular repair is promising. Many customers report improved recovery and reduced stiffness. The quercetin in our formula has been studied for its effects on the enzymes that break down cartilage.

I have chronic fatigue. Is this different from other things I've tried?

If your fatigue is related to cellular energy production (which is common), NAD+ addresses the root cause rather than just masking symptoms. Many women with long-standing fatigue have found relief when other approaches failed, because this works at the mitochondrial level where energy is actually made.

Can this help with weight management?

NAD+ plays a role in metabolism, and many customers report improved energy for exercise and better sleep (both important for weight management).

 

 However, Thryve is not specifically a weight loss supplement—it's designed to restore cellular function, which can support overall health and vitality.

Ordering and Guarantee

How long does shipping take?

We offer free shipping on all orders, with standard delivery in 3-5 business days within the US. Express shipping options are available at checkout for faster delivery.

What's your return policy?

We offer a 30-day money-back guarantee. If you're not completely satisfied with your results, return the bottles (even if empty) within 60 days for a full refund. No questions asked.

Do you offer subscriptions or bulk discounts?

Yes! Our subscription program offers 15% savings and ensures you never run out. You can modify or cancel anytime. We also offer bundle discounts for 3 and 6-month supplies.

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Don't Let Another Year Slip Away

The women who feel and look 10 years younger than their age aren't lucky. They're not genetically blessed.

 

They just have one crucial advantage: their cells have the fuel they need to function properly.

 

You can have that same advantage.

References

1.https://www.cdc.gov/nchs/products/databriefs/db405.htm#:~:text=women%20than%20men.-,The%20age%2Dadjusted%20prevalence%20of%20osteoporosis%20at%20either%20the%20femur,higher%20among%20women%20than%20men.

2. https://www.mdpi.com/1422-0067/25/22/12139#:~:text=Likewise%2C%20androgens%20play%20a%20critical,and%20RANKL%2C%20which%20promote%20osteoclastogenesis.

3.https://www.spandidos-publications.com/10.3892/mmr.2017.6168#:~:text=OPG%2C%20which%20is%20a%20decoy,RANK%20(11%2C12).

4.https://pmc.ncbi.nlm.nih.gov/articles/PMC10608105/#:~:text=The%20RANK%E2%80%93RANKL%E2%80%93OPG%20System,%2C%20Immunity%2C%20and%20Cancer%20%2D%20PMC

5. https://www.longdom.org/open-access/postmenopausal-osteoporosis-causes-mechanisms-risks-diagnosis-treatment-and-prevention-guide1103308.html#:~:text=As%20bone%20mass%20declines%2C%20the,or%20even%20during%20daily%20activities.

6.https://pubmed.ncbi.nlm.nih.gov/35193674/

7.https://pmc.ncbi.nlm.nih.gov/articles/PMC12338550/#:~:text=Abstract,ATP%20generation%20through%20NADH%20oxidation.

8.https://pmc.ncbi.nlm.nih.gov/articles/PMC7442590/#:~:text=In%20humans%2C%20NAD%2B%20concentration%20has,as%20compared%20to%20newborns15.

9.https://pmc.ncbi.nlm.nih.gov/articles/PMC3139257/#:~:text=The%20mean%20age%20of%20this,group%20more%20than%2060%20years.

10. https://pubmed.ncbi.nlm.nih.gov/40053115/

11.https://www.endocrine.org/patient-engagement/endocrine-library/menopause-and-bone-loss#:~:text=Research%20indicates%20that%20up%20to,a%20fracture%20during%20their%20lifetime.

12. https://pubmed.ncbi.nlm.nih.gov/32564438/

13.https://pmc.ncbi.nlm.nih.gov/articles/PMC12338550/#:~:text=Loss%20of%20estrogens%20at%20menopause,the%20osteoclast%20lineage1%E2%80%934.https://pubmed.ncbi.nlm.nih.gov/32564438/

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